Blood component transfusion in hematopoietic cell transplant recipients in the immediate post-transplant period

Recipient ABO type	Donor type O		Donor type A		Donor type B		Donor type AB
Recipient ABO type	RBC type	FFP/PLT type	RBC type	FFP/PLT type	RBC type	FFP/PLT type	RBC type	FFP/PLT type
O	O	Any type	O	A or AB	O	B or AB	O	AB
A	O	A or AB	A or O	A or AB	O	AB	A or O	AB
B	O	B or AB	O	AB	B or O	B or AB	B or O	AB
AB	O	AB	A or O	AB	B or O	AB	AB, A, B, or O	AB

Recipient Rh	Donor Rh-negative		Donor Rh-positive
Recipient Rh	RBC Rh	PLT Rh	RBC Rh	PLT Rh
Rh positive	Negative	See note	Positive	See note
Rh negative	Negative	See note	Negative	See note

HCT recipients who receive HSCs of a different blood type may have chimerism in the immediate post-transplant period. The goals of component selection are to minimize risks of RBC hemolysis and to optimize hematopoiesis from donor cells. Rh(D)-positive recipients with Rh(D)-negative donors receive Rh(D)-negative RBCs and granulocytes. Rh(D)-negative recipients with Rh(D)-positive donors receive Rh(D)-negative RBCs and granulocytes. Platelets should be of the ABO type listed if available. Refer to UpToDate topics on pretransfusion testing, transfusion, and management in the immediate post-HCT period for additional details.

RBC: red blood cell; FFP: fresh frozen plasma; PLT: platelets; Rh: Rh(D); HCT: hematopoietic cell transplant; HSCs: hematopoietic stem cells.

Graphic 99896 Version 3.0

خرید پکیج

Blood component transfusion in hematopoietic cell transplant recipients in the immediate post-transplant period