Pyramid profile of risk stratification model currently used to identify patients at the highest sudden cardiac death (SCD) risk who may be candidates for an implantable cardioverter-defibrillator (ICD)

Major and minor risk markers appear in boxes at the left. At the right are the results of ICD therapy in 730 children, adolescents, and adults assembled from two registry studies.

BP: blood pressure; CAD: coronary artery disease; EF: ejection fraction; ICD: implantable cardioverter-defibrillator; LV: left ventricular; LGE: late gadolinium enhancement; LVH: left ventricular hypertrophy; NSVT: nonsustained ventricular tachycardia; SD: sudden death; VT/VF: ventricular tachycardia/ventricular fibrillation.
* Extensive LGE is a novel primary risk marker that can also be used as an arbitrator when conventional risk assessment is ambiguous.
¶ SD events are uncommon after 60 years of age, even with conventional risk factors.

Reproduced from: Maron B, Ommen S, Semsarian C. Hypertrophic cardiomyopathy: Present and future, with translation into contemporary cardiovascular medicine. J Am Coll Cardiol 2014; 64:83. Illustration used with the permission of Elsevier Inc. All rights reserved.

Graphic 99534 Version 2.0

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Pyramid profile of risk stratification model currently used to identify patients at the highest sudden cardiac death (SCD) risk who may be candidates for an implantable cardioverter-defibrillator (ICD)