Acute effect of altitude on oxygen saturation and arterial blood gas values

Population	Altitude (meters)	Altitude (feet)	P_B (mm Hg)	PaO₂ (mm Hg)	SaO₂ (%)	PaCO₂ (mm Hg)
Altitude residents	1646	5400	630	73 (65-83)	95.1 (93-97)	35.6 (30.7-41.8)
Acute exposure	2810	9219	543	60 (47.4-73.6)	91 (86.6-95.2)	33.9 (31.3-36.5)
	3660	12,008	489	47.6 (42.2-53)	84.5 (80.5-89)	29.5 (23.5-34.3)
	4700	15,420	429	44.6 (36.5-47.5)	78 (70.8-85)	27.1 (22.9-34)
	5340	17,520	401	43.1 (37.6-50.4)	76.2 (65.4-81.6)	25.7 (21.7-29.7)
	6140	20,144	356	35 (26.9-40.1)	65.6 (55.5-73)	22 (19.2-24.8)
Subacute exposure	6500	21,325	346	41.1 ± 3.3	75.2 ± 6	20 ± 2.8
	7000	22,966	324	–	–	–
	8000	26,247	284	36.6 ± 2.2	67.8 ± 5	12.5 ± 1.1
	8400	27,559	272	24.6 ± 5.3	54	13.3
	8848	29,029	253	30.3 ± 2.1	58 ± 4.5	11.2 ± 1.7
	8848	29,029	253	30.6 ± 1.4	–	11.9 ± 1.4

P_B: barometric pressure; PaCO₂: arterial partial pressure of carbon dioxide; PaO₂: arterial partial pressure of oxygen; SaO₂: arterial oxygen saturation.
* Data are mean values and (range) and were obtained in subjects 20 to 40 years of age during the first one to two days of arriving at altitude (acute exposure) and associated with good acclimatization (subacute exposure).

Data from:

Loeppky JA, Caprihan A, Luft UC. VA/Q inequality during clinical hypoxemia and its alterations. In: Shiraki K, Yousef, MK (Eds). Man in Stressful Environments, CC Thomas, Springfield, Il, 1987, p. 199.
McFarland RA, Dill DB. A comparative study of the effects of reduced oxygen pressure on man during acclimatization. J Aviat Med 1938; 9:18.

Reproduced from: Hackett PH, Roach RC. High-altitude medicine and physiology. In: Auerbach PS (Ed). Wilderness Medicine, 6th edition, Elsevier Mosby, Philadelphia, 2012. Table used with the permission of Elsevier Inc. All rights reserved.

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Acute effect of altitude on oxygen saturation and arterial blood gas values