Author | Age | Number of patients | PFS (months) | OS | Postoperative mortality | Postoperative complications | Primary surgery | NACT selected |
Marchetti, 1993 | ≥65 years | 29 | NA | 19.2 months | 3 (10.3%) | NA | 28 (96.6%) | 1 (3.4%) |
Susini, 1999 | ≥70 years | 51 | NA | NA | NA | NA | 51 (100%) | Study exclusion |
Cloven, 1999 | ≥80 years | 18 | NA | 6 months | 2 (11.1%) |
| 16 (88.9%) | 3 (16.7%) |
Bruchim, 2002 | ≥70 years | 46 | NA | NA | 2 (4.3%) | NA | 25 (54.3%) | 13 (43.3%) |
Wright, 2004 | ≥70 years | 46 | NA | NA | 0 |
| 46 (100%) | Study exclusion |
Uyar, 2005 | ≥70 years | 131 | NA | 70 to 79 years: 52 months ≥80 years: 36 months p = 0.07 | NA |
| 105 (80%) | 26 (20%) |
Alphs, 2006 | ≥75 years | 78 | NA | 19 months | 7 (9%) |
| 78 (100%) | Study exclusion |
Moore, 2008 | ≥80 years | 85 | NA | 1° surgery: two-year survival 51% 1° chemo: Two-year survival 27% | 9 (13%) |
| 68 (80%) | 17 (20%) |
Moore, 2009 | ≥80 years | 39 | NA | NA | NA | NA | 39 (100%) | Study exclusion |
McLean, 2010 | ≥80 years | 34 | NA | 24 months | 0 |
| 27 (79.4%) | 7 (20.6%) |
Chereau, 2011 | ≥70 years | 29 | Two-year: 35% Five-year: 23% | Five-year: 55% | 1 (3.4%) |
| 29 (100%) | Study exclusion |
Langstraat, 2011 | ≥65 years | 280 | NA | NA | 12 (4.3%) | Overall: 32 (11.4%) | 280 (100%) | Study exclusion |
Fanfani, 2012 | ≥65 years | 164 | 65 to 74 years: 12 months ≥75 years: 21 months | NA | 0 | Overall: 65 to 74 years: 11 (11.2%) ≥75 years: 8 (25%) | 75 (45.7%) | 89 (54.3%) |
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