Indications for AVR for chronic AR

For the strength of recommendations: Class I means the procedure/treatment should be performed/administered. Class IIa means it is reasonable to perform the procedure/administer treatment. Class IIb means the procedure/treatment may be considered. Class III means that procedure or treatment is not useful/effective and may be harmful.
For the level of evidence: Level A means multiple populations evaluated; data derived from multiple randomized clinical trials or meta-analyses. Level B means limited populations evaluated; data derived from a single randomized trial or nonrandomized studies. Level C means very limited populations evaluated; only consensus opinion of experts, case studies, or standard of care.