| Grading terminology | Criteria | | Semiquantitative | Descriptive | Lymphocytic piecemeal necrosis | Lobular inflammation and necrosis | | 0 | No activity | None | None | | 1 | Minimal activity | Minimal, patchy | Minimal: occasional spotty necrosis | | 2 | Mild activity | Mild, involving some or all portal tracts | Mild: little hepatocellular damage | | 3 | Moderate activity | Moderate, involving all portal tracts | Moderate: noticeable hepatocellular change | | 4 | Severe activity | Severe, may have bridging necrosis | Severe: prominent diffuse hepatocellular damage | | | Semiquantitative | Descriptive | Criteria | | 0 | No fibrosis | Normal connective tissue | | 1 | Portal fibrosis | Fibrous portal expansion | | 2 | Periportal fibrosis | Periportal or rare portal-portal septa | | 3 | Septal fibrosis | Fibrous septa with architectural distortion; no obvious cirrhosis | | 4 | Cirrhosis | Cirrhosis | |
