ﺑﺎﺯﮔﺸﺖ ﺑﻪ ﺻﻔﺤﻪ ﻗﺒﻠﯽ
خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 2 مورد

Antibiotics for asymptomatic bacteriuria and cystitis in pregnancy

Antibiotics for asymptomatic bacteriuria and cystitis in pregnancy
Antibiotic Dose Duration Notes
Amoxicillin 500 mg orally every 8 hours or
875 mg orally every 12 hours		 5 to 7 days
  • Resistance may limit its utility among gram-negative pathogens.
Amoxicillin-clavulanate 500 mg orally every 8 hours or
875 mg orally every 12 hours		 5 to 7 days  
Cefpodoxime 100 mg orally every 12 hours 5 to 7 days  
Cephalexin 250 to 500 mg orally every 6 hours 5 to 7 days  
Fosfomycin 3 g orally as single dose  
  • Does not achieve therapeutic levels in the kidneys so should not be used if pyelonephritis is suspected.
Nitrofurantoin 100 mg orally every 12 hours 5 to 7 days
  • Does not achieve therapeutic levels in the kidneys, so should not be used if pyelonephritis is suspected.
  • Typically avoided during the first trimester and at term; however, it is an appropriate alternative during these periods when other options cannot be used.
Pivmecillinam 185 mg pivmecillinam base orally 3 times daily (dose approved in the United States) 3 to 7 days
  • Should not be used if pyelonephritis is suspected.
  • Dosing varies by region, and overall, there is no evidence clearly demonstrating that one regimen is superior to the other. The dose is also variably expressed as either pivmecillinam base or pivmecillinam HCl salt; 185 mg pivemecillinam base is equivalent to 200 mg pivmecillinam HCl.
  • We generally use the dose approved in the United States; however, for directed therapy of MDR organisms (eg, ESBL-producing isolates that are susceptible to pivmecillinam), it is reasonable to use the higher dose.
  • Use during pregnancy may result in a false-positive test for isovaleric acidemia as part of newborn screening.
400 mg pivmecillinam HCl orally 3 times daily (dose recommended in some European countries) 3 to 5 days
Trimethoprim-sulfamethoxazole 800/160 mg (1 double-strength tablet) every 12 hours 3 days
  • Typically avoided during the first trimester and at term; however, it is an appropriate alternative during these periods when other options cannot be used.
The durations listed in the table are based on data from studies conducted in both nonpregnant and pregnant women.
ESBL: extended-spectrum beta-lactamase; MDR: multidrug-resistant.
Graphic 98083 Version 11.0