Version May 2024
| If you had SJS or TEN with one of these, you must avoid all other medicines that are in the same group and closely related medicines | |
| Generic name | US brand names |
| GROUP 1: Used to prevent gout attacks | |
| Allopurinol | Aloprim, Zyloprim |
| There are no known closely related medicines to allopurinol | |
| GROUP 2: Some anti-seizure medicines – Used to prevent seizures or pain | |
| Carbamazepine | Tegretol, Carbatrol, Epitol, Equetro |
| Fosphenytoin | Cerebyx |
| Lamotrigine | Lamictal |
| Phenobarbital (phenobarbitone) | Luminal |
| Phenytoin | Dilantin, Dilantin Infatabs, Phenytek |
| Primidone | Mysoline |
| Following are closely related to above anti-epileptic drugs and must also be avoided: | |
| Eslicarbazepine | Aptiom |
| Felbamate | Felbatol |
| Oxcarbazepine | Trileptal, Oxtellar XR |
| Phenobarbital combinations for stomach problems | Donnatal |
| Zonisamide | Zonegran |
| GROUP 3: "Sulfa" antibiotics – Used for treating infections | |
| Trimethoprim-sulfamethoxazole (also called cotrimoxazole and TMP-SMX) | Bactrim, Septra, Sulfatrim |
| Sulfadiazine | No brand (generic only) |
| Sulfadoxine and pyrimethamine | Fansidar |
| Following are closely related to above "sulfa" antibiotics and must also be avoided: | |
| Erythromycin-sulfisoxazole | Pediazole |
| Silver sulfadiazine cream | Silvadene, SSD, Thermazene |
| Sulfacetamide-containing skin products including cleansers, creams, foams, gels, lotions, pads, washes, and shampoos | APOP, AVAR, Klaron, Claris, Ovace, Plexion, Prascion, Rosanil, Seb-Prev, SSS, Sulfacet-R, Sulfacleanse, Sumadan, Sumaxin, Verti-sulf, Zencia, others |
| Sulfacetamide-containing eye drops, eye ointments, and ear drops | Bleph-10, Blephamide |
| Sulfacetamide, sulfanilamide, and/or sulfathiazole vaginal products | AVS, VVS, Triple Sulfa Vaginal |
| Sulfasalazine used for treating colitis or rheumatoid arthritis | Azulfidine |
| GROUP 4: Nonsteroidal drugs (also called "NSAIDs") – Used to treat pain or inflammation | |
| Meloxicam | Mobic |
| Piroxicam | Feldene |
| Tenoxicam (not available in the US) | Brand depends on country |
| Other NSAIDs should in general be avoided: NOTE – Carefully check all medicine labels, including pain relievers, cough or cold medicines, shots, ointments, creams, gels, patches, eye drops, and nose sprays to be sure they contain no NSAID. | |
| Ibuprofen | Advil, Motrin |
| Naproxen | Aleve |
| Celecoxib | Celebrex |
| Ketorolac | Toradol, Sprix, Acular, Acuvail |
| Diclofenac | Voltaren, Flector, Pennsaid |
| Indomethacin | Indocin |
| NOTE – Many other prescription and non-prescription medicines contain NSAIDs. Have your doctor, nurse, or pharmacist confirm that any medicine you are thinking of using does not contain an NSAID. | |
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