Structure of the glycosylphosphatidylinositol anchor on a RBC

Illustration of GPI-linked protein on red blood cell surface; the GPI linkage is deficient in paroxysmal nocturnal hemoglobinuria (PNH).

GPI: Glycosylphosphatidylinositol; RBC: red blood cell.

Courtesy of Robert A Brodsky, MD.

Graphic 96559 Version 2.0