Epidural pain management; surgical anesthesia
Note: Dose ranges are not intended to guide prescribing; consult local prescribing information for additional dosage and administration information.
Children >6 months to <12 years: Surgical anesthesia: Local infiltration (Ilioinguinal/iliohypogastric block): 0.5 mL/kg/side of 0.25% solution (maximum: 1.25 mg/kg/side) or 0.25 mL/kg/side of 0.5% solution (maximum: 1.25 mg/kg/side).
Adults:
Surgical anesthesia:
Dental: 5 to 10 mL of 0.5% to 0.75% solution.
Epidural:
Cesarean section: 15 to 30 mL of 0.5% solution; maximum single dose: 150 mg.
Surgery, not cesarean section: 10 to 20 mL of 0.5% to 0.75% solution; maximum single dose: 150 mg; prolonged surgeries may require a maximum cumulative dose of 400 mg/24 hours.
Intrathecal: 3 mL of 0.5% solution.
Local infiltration: 1 to 60 mL of 0.25% solution; maximum: 150 mg.
Ophthalmic (peribulbar block): 5 to 15 mL of 0.75% solution.
Peripheral nerve: 1 to 40 mL of 0.25% solution or 1 to 30 mL of 0.5% solution; maximum: 150 mg.
Pain management:
Labor pain (epidural bolus): 6 to 20 mL of 0.25% solution.
Labor pain (epidural infusion): 10 to 15 mL/hour of 0.0625% solution or 4 to 10 mL/hour of 0.125% solution (maximum: 12.5 mg/hour; a maximum cumulative dose of 400 mg per 24 hours is recommended).
Peri- and postoperative pain (epidural infusion): 10 to 15 mL/hour of 0.0625% solution, or 10 to 15 mL/hour of 0.125% solution, or 5 to 7.5 mL/hour of 0.25% solution (maximum rate: 18.75 mg/hour; maximum cumulative dose: 400 mg/24 hours; however, postoperative doses up to 570 mg/24 hours have been well tolerated).
Product available in various countries; not currently available in the US
Solution, Infusion/Injection: 2.5 mg/mL, 5 mg/mL, 7.5 mg/mL (10 mL)
Solution, Infusion [premixed]: 0.625 mg/mL, 1.25 mg/mL (100 mL, 200 mL)
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