Leukocytoclastic vasculitis of lower extremities with histology

Cutaneous vasculitis most often presents as palpable purpura that is typically a manifestation of benign, localized, self-limited cutaneous disease, often triggered by preceding infection or drug ingestion. Histologically, it is identified by a neutrophilic infiltrate surrounding and disrupting small vessels (postcapillary venules) associated with fibrin deposits and nuclear debris (leukocytoclasia). Extravasated red blood cells, purpura, will be found in the adjacent dermis.