(For additional information
see "Gentamicin (topical): Patient drug information" and
see "Gentamicin (topical): Pediatric drug information")
For abbreviations, symbols, and age group definitions used in Lexicomp (
show table)
Pharmacologic Category
-
Antibiotic, Aminoglycoside;
-
Antibiotic, Topical
Dosing: Adult
Dermatologic infections
Dermatologic infections:
Topical: Apply 3 to 4 times daily to affected area.
Dosing: Kidney Impairment: Adult
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
Dosing: Hepatic Impairment: Adult
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
Dosing: Older Adult
Refer to adult dosing.
Dosing: Kidney Impairment: Pediatric
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
Dosing: Hepatic Impairment: Pediatric
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
Adverse Reactions
The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified.
Frequency not defined.
Dermatologic: Erythema, pruritus
Contraindications
Hypersensitivity to gentamicin or any component of the formulation
Warnings/Precautions
Concerns related to adverse effects:
• Superinfection: Prolonged use may result in fungal or bacterial superinfection; discontinue if superinfection is noted.
• Sensitization: Topical use has been associated with local sensitization (redness, irritation); discontinue if sensitization is noted.
Other warnings/precautions:
• Long-term use: Not intended for long-term therapy.
Dosage Forms: US
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Cream, External:
Generic: 0.1% (15 g, 30 g)
Ointment, External:
Generic: 0.1% (15 g, 30 g)
Generic Equivalent Available: US
Yes
Pricing: US
Cream (Gentamicin Sulfate External)
0.1% (per gram): $3.29
Ointment (Gentamicin Sulfate External)
0.1% (per gram): $3.29
Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.
Administration: Adult
Topical: For external use only; not for ophthalmic use. Apply gently to affected area; may cover with gauze dressing. Remove crust of impetigo contagiosa prior to application.
Administration: Pediatric
For external topical use only; not for ophthalmic use. Apply a small amount gently to the cleansed affected area; may cover with gauze dressing.
Use: Labeled Indications
Dermatologic infections: Topical treatment of superficial dermatologic infections
Medication Safety Issues
Sound-alike/look-alike issues:
Gentamicin may be confused with gentian violet, kanamycin, vancomycin
Metabolism/Transport Effects
None known.
Drug Interactions
There are no known significant interactions.
Mechanism of Action
Interferes with bacterial protein synthesis by binding to 30S ribosomal subunit resulting in a defective bacterial cell membrane
Pharmacokinetics (Adult Data Unless Noted)
Absorption: Systemic absorption is reported following topical application to burn patients (Sawchuk 1980).
Brand Names: International
International Brand Names by CountryFor country code abbreviations (
show table)
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(AE) United Arab Emirates: Cidomycin | Garamycin | Gental | Genticin;
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(AR) Argentina: Gentaderm | Gentamicin | Gentamicina fabra | Gentamina | Gentaren | Gentum | Metadyne | Plurisemina | Rupegen | Ultradermis;
-
(AT) Austria: Refobacin;
-
(BD) Bangladesh: Genacyn | Genticin | Gentin | Gentosep | Monamycin;
-
(BE) Belgium: Geomycine;
-
(BG) Bulgaria: Gentamicin medphano | Gentamycin;
-
(BR) Brazil: Garacin | Garamicina | Gentamicina | Gentamil;
-
(CH) Switzerland: Garamycin;
-
(CL) Chile: Gentalyn | Gentamicina | Gevracilina;
-
(CO) Colombia: Garamicina | Gentacrem | Gentamas | Gentamicina | Micigent;
-
(DE) Germany: Gentamycin | Infectogenta | Refobacin | Sulmycin;
-
(DO) Dominican Republic: Garamicin | Garamicina | Gen forte | Gentaderm | Gentamicina | Gentax;
-
(EC) Ecuador: Garamicina | Gentaderm | Gentamax | Gentamicina;
-
(EE) Estonia: Garamycin | Gentamycin;
-
(EG) Egypt: Apigent | Biogentacin | Cidomycin | Farcocin | Garamycin | Genmycin | Gentaderm | Gentamicin | Nerhamicin | Refobacin;
-
(ES) Spain: Gentamival | Gevramycin;
-
(FI) Finland: Garamycin;
-
(FR) France: Gentalline;
-
(GB) United Kingdom: Cidomycin | Genticin;
-
(GR) Greece: Diakarmon | Genta;
-
(HK) Hong Kong: Garamycin | Gentacin | Gentamicin | Gentamycin | Gentopic;
-
(HU) Hungary: Gentamycin;
-
(ID) Indonesia: Balticin | Bioderm | Dermabiotik | Dermagen | Garabiotic | Garamycin | Garapon | Gentalex | Gentamerck | Gentamicin | Gentamycin | Genticid | Gentiderm | Gragenta | Ikagen | Konigen | Licogenta | Nichogencin | Ottogenta | Paranten | Pyogenta | Rogencin | Sagestam | Salticin;
-
(IE) Ireland: Cidomycin | Genticin;
-
(IL) Israel: Garamycin | Gentatrim;
-
(IN) India: Dermycin | Gentamycin | Gentamycin sulphate | Gentlee | L-genta | Laramycin | Lyramycin | Merigenta | Supragent;
-
(IQ) Iraq: As ginoden | Genidin;
-
(IT) Italy: Ciclozinil | Eutopic | Genbrix | Gentacream | Gentalyn | Gentamicina | Gentamicina Almus | Gentamicina alter | Gentamicina doc | Gentamicina eg | Gentamicina idi farmaceutici | Gentamicina ratiopharm | Nemalin | Tacigen;
-
(JP) Japan: Gentacin;
-
(KE) Kenya: Gentosep;
-
(KR) Korea, Republic of: Ahn gook gentamicin sulfate | Gentacin | Gentamicin | Zentacin;
-
(KW) Kuwait: Cidomycin | Garamycin;
-
(LB) Lebanon: Cidomycin | Garamycin;
-
(LT) Lithuania: Gentamycin;
-
(LU) Luxembourg: Geomycine;
-
(LV) Latvia: Gentamycin;
-
(MA) Morocco: Gentalline;
-
(MX) Mexico: Garamicina;
-
(MY) Malaysia: Beagenta | Dermogen | Garamycin | Gentacin | Gentamicin | Gentamycin | Lisarin | Miramycin;
-
(NG) Nigeria: Rgi gentamicin cream;
-
(NL) Netherlands: Garamycin;
-
(NO) Norway: Infectogenta;
-
(PE) Peru: Gentalyn | Gentamicina;
-
(PH) Philippines: Garamycin;
-
(PK) Pakistan: Atcogen | Cingenta | G-mycin | Gentalek | Gentamicin | Gentamycin | Genticyn | Gentriderm | Karmagen | Mafgent | Swigen | Valigent;
-
(PL) Poland: Gentamycin;
-
(PR) Puerto Rico: Garamycin;
-
(PT) Portugal: Garalone | Gentamicina | Gentocil;
-
(PY) Paraguay: Cremoterapico biotic | Gental g | Gentaland biotic | Gentamina;
-
(QA) Qatar: Biogentacin | Farcocin | Garamycin | Genta | Gental | Gentapar | Gevramycin | Refobacin;
-
(RO) Romania: Gentatrim;
-
(RU) Russian Federation: Garamycin;
-
(SA) Saudi Arabia: Cidomycin | Garamycin;
-
(SG) Singapore: Dermogen | Garamycin | Gentamicin | Gentamycin | Gentopic | Miramycin;
-
(TH) Thailand: Faracin | Garamycin | Gencidal | Gencin | Genda | Genmocin | Gentacin | Gentaderm | Gental | Gentamycin | Gentramycin | Gentrex | Grammicin | Grammixin | Miramycin | Pharacin | Skinfect | Versigen;
-
(TR) Turkey: Garamycin | Gentaderm | Gentamycin;
-
(TW) Taiwan: Gamicin | Garamycin | Gencin | Genrite | Genta | Gentacin | Gentamicin | Gentamycin | Gentatrim | Gentermay;
-
(UA) Ukraine: Gentamycin;
-
(UG) Uganda: Farcocin;
-
(UY) Uruguay: Gentamina;
-
(VE) Venezuela, Bolivarian Republic of: Catogen | Gentamicina | Gentisul;
-
(ZA) South Africa: Garamycin;
-
(ZM) Zambia: Gentamicin
