NCI CTCAE v5.0 proteinuria

Adverse event	Grade 1	Grade 2	Grade 3	Grade 4	Grade 5
Proteinuria	1+ proteinuria on dipstick; urinary protein <1.0 g/24 hours	Adult: 2+ and 3+ proteinuria on dipstick; urinary protein 1.0 to 3.4 g/24 hours	Adult: Urinary protein ≥3.5 g/24 hours
Proteinuria	1+ proteinuria on dipstick; urinary protein <1.0 g/24 hours	Pediatric: Urine protein/creatinine (P/C) ratio 0.5 to 1.9	Pediatric: Urine protein/creatinine (P/C) ratio >1.9

Proteinuria is characterized by laboratory test results that indicate the presence of excessive protein in the urine. It is predominantly albumin, but can also include globulin. A 24-hour urine collection to quantify the degree of proteinuria takes precedence over a dipstick result.

NCI CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events.

Reproduced from: Common Terminology Criteria for Adverse Events (CTCAE), Version 5.0, November 2017, National Institutes of Health, National Cancer Institute. Available at: https://ctep.cancer.gov/protocoldevelopment/electronic_applications/docs/CTCAE_v5_Quick_Reference_8.5x11.pdf (Accessed March 27, 2018).

Graphic 91255 Version 6.0

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NCI CTCAE v5.0 proteinuria