Renal syndromes associated with NSAID use

Acute kidney injury (hemodynamically mediated or acute tubular necrosis)

Acute interstitial nephritis

Nephrotic syndrome (minimal change disease or membranous nephropathy)

Hyponatremia

Hyperkalemia/type 4 renal tubular acidosis

Hypertension/edema

Acute papillary necrosis

Chronic tubulointerstitial nephritis/analgesic nephropathy

Uroepithelial malignancy

NSAID: nonsteroidal antiinflammatory drug.

Source: Clive DM, Stoff JS. Renal syndromes associated with nonsteroidal antiinflammatory drugs. N Engl J Med 1984; 310:563.

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