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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Autoantibodies and associated neuropathies

Autoantibodies and associated neuropathies
Antibody Clinical features of associated neuropathy Associated systemic disease
GM1 Multifocal motor neuropathy; may also be elevated in motor neuron disease, Guillain-Barré syndrome and its variants None
MAG; SGPG Demyelinating neuropathy, most often with distal predominantly sensory symptoms (DADS phenotype) IgM monoclonal gammopathy of undetermined significance (MGUS)
GQ1b Miller Fisher syndrome; Bickerstaff encephalitis, pharyngeal-cervical-brachial weakness; "anti-GQ1b antibody syndrome" None
GD1a Axonal Guillain-Barré syndrome  
GD1b Sensory-predominant neuropathy; motor neuron disease; Guillain-Barré syndrome None
Sulfatide Sensory-predominant neuropathy None
Galopin (IgM kappa) Gait ataxia with late onset polyneuropathy (GALOP) syndrome None
Hu (ANNA-1) Sensory neuronopathy; autonomic and sensorimotor polyneuropathy Cancer, typically small-cell lung cancer (SCLC). May also be associated with limbic encephalitis.
CV2/CRMP-5; amphiphysin; Ri (ANNA-2), ANNA-3; N-type calcium channel antibodies Sensorimotor polyneuropathy Cancer, typically SCLC, thymoma, breast cancer. Antibodies are associated with other neurologic syndromes including limbic encephalitis.
C-ANCA; P-ANCA Painful mononeuritis multiplex; distal symmetric polyneuropathy less common Systemic vasculitis: Churg-Strauss; polyarteritis nodosa; granulomatosis with polyangiitis (Wegener)
ANA; RF Painful neuropathy; mononeuritis multiplex Rheumatoid arthritis; systemic vasculitis
Ro/SSA; La/SSB Painful sensory, predominantly small-fiber, neuropathy; sensory neuronopathy Sjögren syndrome
Gliadin; endomysial; tTG (tissue trans-glutaminase) Mild distal sensory polyneuropathy Celiac disease
Contactin-1 Subacute neuropathy with ataxia and cranial nerve impairments None
Neurofascin-155 Distal-predominating neuropathy with sensory ataxia and tremor None
Contactin-associated protein 1 Acute or subacute sensory neuropathy with ataxia, cranial nerve impairments, tremor, and neuropathic pain None
Neurofascin 140/186 Severe motor neuropathy with cranial nerve and respiratory involvement, dysautonomia, and nephrotic syndrome None
ANA: antinuclear antibodies; ANCA: antineutrophil cytoplasmic antibodies; ANNA: antineuronal nuclear antibodies; CRMP: collapsin response mediator protein; IgM: immunoglobulin M; MAG: myelin-associated glycoprotein; RF: rheumatoid factor; SGPG: sulfoglucuronyl glycosphingolipid; tTG: tissue transglutaminase.
Graphic 89909 Version 4.0

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