Range of normal results for coagulation tests in pregnancy

Test	Normal (reference) range
Test	First trimester	Second trimester	Third trimester
Prothrombin time (seconds)	9.7 to 13.5	9.5 to 13.4	9.6 to 12.9
Activated partial thromboplastin time (seconds)	23.0 to 38.9	22.9 to 38.1	22.6 to 35.0
Platelet count (x10⁹/L)	174 to 391	155 to 409	146 to 429
Fibrinogen (mg/dL)	244 to 510	291 to 538	301 to 696
D-dimer (micrograms/mL)	0.05 to 0.95	0.32 to 1.29	0.13 to 1.7

Data from: Abbassi-Ghanavati M, Greer LG. Reference Table of Normal Laboratory Values in Uncomplicated Pregnancies. In: Cunningham FG, Leveno KJ, Bloom S, Hauth JC, Rouse DJ, Spong CY. Williams Obstetrics, 23rd Edition. New York: McGraw-Hill, 2010.

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