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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
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Symptoms associated with colorectal cancer

Symptoms associated with colorectal cancer
Symptom DOR*
(95% CI*)		 AUC Sensitivity
(95% CI)		 1-specificity
(95% CI)		 LR+
(95% CI)		 LR–
(95% CI)
Rectal bleedingΔ 2.6

(1.9-3.6)

p<0.001		 0.66 0.46
(0.38-0.55)		 0.25
(0.19-0.31)		 1.9
(1.5-2.3)		 0.7
(0.6-0.8)
Blood mixed with stool 3.1

(2.0-4.8)

p<0.001		 0.68 0.49
(0.30-0.69)		 0.24
(0.13-0.40)		 2.1
(1.5-2.8)		 0.7
(0.5-0.9)
Blood: dark red 3.9

(1.7-9.2)

p = 0.004		 0.71 0.29
(0.09-0.65)		 0.10
(0.03-0.28)		 3.1
(1.6-6.0)		 0.8
(0.6-1.1)
Change in bowel habit 1.5

(0.8-2.8)

p = 0.16		 0.57 0.32
(0.21-0.46)		 0.24
(0.15-0.35)		 1.4
(0.9-2.1)		 0.9
(0.7-1.1)
Constipation 1.1

(0.8-1.5)

p = 0.48		 0.52 0.12
(0.08-0.18)		 0.11
(0.07-0.16)		 1.1
(0.8-1.5)		 1.0
(1.0-1.0)
Diarrhea 0.9

(0.4-1.7)

p = 0.65		 0.47 0.15
(0.07-0.28)		 0.17
(0.09-0.29)		 0.9
(0.5-1.6)		 1.0
(0.9-1.1)
Abdominal pain 0.7

(0.5-1.1)

p = 0.12		 0.45 0.19
(0.13-0.28)		 0.24
(0.17-0.33)		 0.8
(0.6-1.1)		 1.1
(1.0-1.2)
Weight loss 2.9

(1.6-5.0)

p = 0.001		 0.67 0.20
(0.12-0.31)		 0.08
(0.05-0.13)		 2.5
(1.5-4.0)		 0.9
(0.8-1.0)
LR+: the likelihood ratio of having colorectal cancer in the presence of the symptom; LR–: the likelihood ratio of having colorectal cancer in the absence of the symptom.
* DOR: diagnostic odds ratio. No association between symptom and cancer if DOR = 1.
¶ AUC: Area Under the receiver operating characteristic Curve. No association between symptom and cancer if AUC = 0.5.
Δ Bleeding of any type.
Reproduced from: Adelstein B, Macaskill P, Chan SF, et al. Most bowel cancer symptoms do not indicate colorectal cancer and polyps: a systematic review. BMC Gastroenterology 2011; 11:65. Copyright © 2011 Adelstein et al.
Graphic 88734 Version 4.0

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