Organ system | Changes | Implications |
Pulmonary | Decreased vital capacity Decreased forced expiratory volume Smaller alveolar surface area Decreased chest wall compliance | Reduced respiratory reserve |
Cardiac | Decreased cardiac output Decreased sensitivity to catecholamines | Reduced cardiac reserve Vital signs may not reflect severity of injury |
Renal | Decreased glomerular filtration rate Decreased renal mass | Increased risk of traumatic injury Increased risk of contrast-induced nephropathy Increased susceptibility to fluid overload Reduced clearance of certain medications |
Hepatic | Decreased hepatic function | Decreased clearance of certain medications |
Gastrointestinal | Diminished pain sensation Increased laxity of abdominal wall musculature | Potential for significant abdominal injury without peritoneal signs |
Immune | Impaired immune response | Increased risk of infection |
Musculoskeletal | Loss of muscle mass Osteoporosis | Increased risk of fracture |
Neurologic | Decreased autoregulatory capability Brain atrophy | Increased susceptibility to injury from decreased cerebral perfusion Increased risk for occult injury |
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