Histologic features of erythroderma associated with cutaneous T cell lymphoma or inflammatory dermatoses

Morphologic features in representative samples of erythrodermic CTCL and inflammatory dermatoses. A, C, and E show examples of erythrodermic CTCL, whereas B, D, and F are from the EID group.
(A) In this SS, skin biopsy did not allow a definite diagnosis, only showing a perivascular lymphocytic infiltrate without atypical lymphocyte, with an overlying hyperplastic and parakeratotic epidermis with slight spongiosis.
(B) In this erythrodermic drug reaction sample, a common perivascular lymphocytic infiltrate is seen, whereas no interface dermatitis and no apoptotic keratinocytes are identified.
(C) This SS sample shows a very discrete infiltrate in the dermis, but atypical lymphocytes and Pautrier microabcesses can be identified in the epidermis.