Clinical manifestations of acute HIV infection

Features (percent)	Overall (n = 378)	Male (n = 355)	Female (n = 23)	Sexual* (n = 324)	IVDU^¶ (n = 34)
Fever	75	74	83	77	50
Fatigue	68	67	78	71	50
Myalgia	49	50	26	52	29
Skin rash	48	48	48	51	21
Headache	45	45	44	47	30
Pharyngitis	40	40	48	43	18
Cervical adenopathy	39	39	39	41	27
Arthralgia	30	30	26	28	26
Night sweats	28	28	22	30	27
Diarrhea	27	27	21	28	23

This table lists the most frequent clinical findings reported among patients with acute HIV infection from five prospective cohorts.

* Homosexual or heterosexual route of transmission.
¶ IVDU, intravenous drug use as route of transmission.

Reproduced with permission from: Daar ES, Pilcher CD, Hecht FM. Clinical presentation and diagnosis of primary HIV-1 infection. Curr Opin HIV AIDS 2008; 3:10. Copyright © 2008 Lippincott Williams & Wilkins.

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Clinical manifestations of acute HIV infection