Nature of operation | Common pathogens | Recommended antimicrobials | Usual adult dose* | Redose interval¶ |
Elective craniotomy Cerebrospinal fluid shunting procedures Implantation of intrathecal pumps | Staphylococcus aureus, S. epidermidis | Cefazolin | <120 kg: 2 g ≥120 kg: 3 g | 4 hours |
OR vancomycinΔ | 15 mg/kg IV (max 2 g) | 12 hours | ||
OR clindamycin | 900 mg IV | 6 hours |
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