N-serrated pattern of IgG basement membrane zone antibody staining in bullous pemphigoid by DIF microscopy

The positive DIF staining along the basement membrane zone in this section of a perilesional skin specimen demonstrates what is described as an n-serrated linear pattern interspersed with segments of true linear IgG basement membrane zone antibody reactivity. This pattern is associated with bullous pemphigoid, mucous membrane pemphigoid, anti-laminin gamma-1 pemphigoid, and linear IgA bullous dermatosis.