Major clinical manifestations of Gaucher disease (all types) at presentation

Clinical manifestation	Frequency (percent at presentation)
Splenomegaly	85
Hepatomegaly	63
Thrombocytopenia	68
Anemia	34
Bleeding	Common (percent not reported)
Osteopenia	55
Bone pain	33
Pathologic fractures	7
Bone crisis	7
Growth retardation	36

Data from: Charrow J, Andersson HC, Kaplan P, et al. The Gaucher Registry: Demographics and disease characteristics of 1698 patients with Gaucher disease. Arch Intern Med 2000; 160:2835.

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Major clinical manifestations of Gaucher disease (all types) at presentation