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Major clinical manifestations of Gaucher disease (all types) at presentation

Major clinical manifestations of Gaucher disease (all types) at presentation
Clinical manifestation Frequency
(percent at presentation)
Splenomegaly 85
Hepatomegaly 63
Thrombocytopenia 68
Anemia 34
Bleeding Common
(percent not reported)
Osteopenia 55
Bone pain 33
Pathologic fractures 7
Bone crisis 7
Growth retardation 36
Data from: Charrow J, Andersson HC, Kaplan P, et al. The Gaucher Registry: Demographics and disease characteristics of 1698 patients with Gaucher disease. Arch Intern Med 2000; 160:2835.
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