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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
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Medications and toxins associated with acute liver failure

Medications and toxins associated with acute liver failure
Antiinfective
Clavulanic acid/amoxicillin
Sulfonamide (trimethoprim-sulfamethoxazole)
Isoniazid
Minocycline, doxycycline, tetracycline
Nitrofurantoin
Ketoconazole, itraconazole, voriconazole
Rifampin
Macrolides (erythromycin, clarithromycin, azithromycin, roxithromycin)
Pyrazinamide
Quinolones (ciprofloxacin, levofloxacin, norfloxacin)
Cephalosporins
Others
Antiseizure medications
Phenytoin
Valproate*
Carbamazepine
Felbamate
Lamotrigine
Immunomodulators/antiinflammatory
Acetaminophen (APAP)
Methotrexate
Azathioprine
Biological (ie, infliximab, basiliximab, etc)
Nonsteroidal antiinflammatory drugs
Others
Analgesic
Halothane
Sevoflurane
Other
Propylthiouracil (a thionamide)
Amiodarone
Antidepressants:
Trazodone (SSRI)
Monoamine oxidase inhibitors
Tricyclic antidepressants
Recreational drugs
Ecstasy (3,4-methylenedioxyamphetamine [MDMA])
Cocaine
Solvent sniffing (glue)
Others
Complementary, alternative, or herbal medications
Pyrrolizidine alkaloids
Germander (Teucrium polium)
Ma huang
Chaparral
Black cohosh root
Pennyroyal
Kava
Impila (Callilepis laureola)
Chamaeleon gummifer (Atractylis gummifera)
Green tea (Camellia sinensis)
Others
Environmental toxins or industrial solvents
Amatoxin (mushrooms from Amanita sp)
Carbon tetrachloride
Trichloroethylene
2-nitropropane
1,2,3-trichloropropane
More information about medications and herbal therapies are available from the LiverTox website.

SSRI: selective serotonin reuptake inhibitor.

* Patients with unsuspected mitochondrial disease (eg, Alpers-Huttenlocher disease, caused by POLG gene mutations) are particularly at risk for hepatotoxicity from valproate.
Modified with permission from: Squires RH, Alonso EM. Acute liver failure in children. In: Liver Disease in Children, 4th ed, Suchy FJ, Sokol RJ, Balistreri WF (Eds), Cambridge University Press, New York 2012. Copyright © 2012 Cambridge University Press.
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