Prognostic model | Risk groups | Survival in patients not undergoing stem cell transplantation | Survival in patients undergoing stem cell transplantation | |||
Median in months | 5-year survival rate (%)* | Median in months | 4-year survival rate (%)* | |||
Mayo Stage[1,2] | Stage I | Cardiac troponin <0.035 mcg/L and NT-proBNP <332 ng/L | 26 | 28 | Not reached at 40 months | 85¶ |
Stage II | Any 1 factor high | 11 | 12 | Not reached at 40 months | 75¶ | |
Stage III | Cardiac troponin ≥0.035 mcg/L and NT-proBNP ≥332 ng/L | 4 | 8 | 8 | 25¶ | |
Revised Mayo Stage[3] | Stage I | NT-proBNP <1800 ng/L, cardiac troponin T <0.025 mcg/L, and difference between involved and uninvolved serum free light chains <18 mg/dL | 55 | 50 | Not reached | 87 |
Stage II | Any 1 factor high | 19 | 35 | 97 | 72 | |
Stage III | Any 2 factors high | 12 | 20 | 58 | 56 | |
Stage IV | NT-proBNP ≥1800 ng/L, cardiac troponin T ≥0.025 mcg/L, and difference between involved and uninvolved serum free light chains ≥18 mg/dL | 5 | 15 | 22 | 46 |
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