Features identified by the National Comprehensive Cancer Network as risk factors for recurrence of cutaneous squamous cell carcinoma

Location/size*

Poorly defined borders

Recurrent tumors

Immunosuppressed patient

Site of previous radiation therapy or chronic inflammation

Rapidly growing tumor

Neurologic symptoms

Poorly differentiated tumor

Acantholytic (adenoid), adenosquamous, desmoplastic, or metaplastic (carcinosarcomatous) subtypes

Depth ≥2 mm or Clark level IV or V

Perineural, lymphatic, or vascular involvement

* Size ≥20 mm on trunk or extremities (excluding pretibia, hands, feet, nail units, and ankles); size ≥10 mm on cheeks, forehead, scalp, neck, or pretibia; size ≥6 mm on "mask areas" of the face (central face, eyelids, eyebrows, periorbital nose, lips [cutaneous and vermilion], chin, mandible, preauricular and postauricular skin/sulci, temple, ear, genitalia, hands, and feet).

Adapted from: NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines^®): Squamous Cell Skin Cancer, Version 2.2018.

Graphic 83683 Version 5.0

خرید پکیج

Features identified by the National Comprehensive Cancer Network as risk factors for recurrence of cutaneous squamous cell carcinoma