Version May 2024
Hemostasis: Topical: Apply evenly to wound.
There are no dosage adjustments provided in the manufacturer’s labeling.
There are no dosage adjustments provided in the manufacturer’s labeling.
Refer to adult dosing.
The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified. Frequency not defined.
Dermatologic: Skin hyperpigmentation (application site)
There are no contraindications in the manufacturer’s labeling.
Concerns related to adverse effects:
• Hyperpigmentation: May cause heavy pigmentation at application sites, which may result in histologic artifacts (upon rebiopsy) or in radiographic artifacts.
Other warnings/precautions:
• Appropriate use: For external use only. If inadvertent ocular administration occurs wash eye(s) immediately with large amounts of water or normal saline for approximately 15 to 20 minutes or until no evidence of solution remains.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Solution, External:
Astringyn: 259 mg/g (8 g) [contains benzalkonium chloride]
Monsels Ferric Subsulfate: (8 mL, 60 mL)
Yes
Solution (Astringyn External)
259 mg/g (per gram): $2.46
Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.
Topical: For external use only. Avoid contact with eyes. One method for applying ferric subsulfate for dermal use consists of the health care provider placing fingers at the opposite edges of the wound and stretching the skin. The wound is then wiped with gauze, the ferric subsulfate solution applied, and the tension maintained for ~15 seconds.
Hemostatis: Hemostatic in minor surgical procedures.
None known.
There are no known significant interactions.
Ferric subsulfate is used as a hemostatic agent following cervical biopsies (Manca 1997; Tam 2005). May cause vaginal pain if leakage of solution occurs (Tam 2005). A case report also describes use following a miscarriage; fertility was not impaired and a successful pregnancy occurred 7 months later (Disu 2007).
Hemostasis at site of application.
Causes agglutination of surface proteins resulting in hemostasis
Onset: Hemostasis: ≤20 seconds
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