Version May 2024
| RIFLE[1] | AKIN[2] | KDIGO[3] | |
| Diagnostic criteria* | |||
| Increase in serum creatinine of ≥0.3 mg/dL or ≥50% within 48 hours OR Urine output of <0.5 mL/kg/hour for >6 hours | Increase in serum creatinine of ≥0.3 mg/dL within 48 hours or ≥50% within 7 days OR Urine output of <0.5 mL/kg/hour for >6 hours | ||
| Staging criteria | |||
| Risk (RIFLE) or stage 1 (AKIN/KDIGO) | Increase in serum creatinine to 1.5 times baseline OR Urine output of <0.5 mL/kg/hour for 6 to 12 hours | Increase in serum creatinine of ≥0.3 mg/dL or to 150 to 200% baseline OR Urine output of <0.5 mL/kg/hour for 6 to 12 hours | Increase in serum creatinine of ≥0.3 mg/dL or 1.5 to 1.9 times baseline OR Urine output of <0.5 mL/kg/hour for 6 to 12 hours |
| Injury (RIFLE) or stage 2 (AKIN/KDIGO) | Increase in serum creatinine to 2 times baseline OR Urine output of <0.5 mL/kg/hour for 12 to 24 hours | Increase in serum creatinine to 200 to 300% baseline OR Urine output of <0.5 mL/kg/hour for 12 to 24 hours | Increase in serum creatinine to 2 to 2.9 times baseline OR Urine output of <0.5 mL/kg/hour for 12 to 24 hours |
| Failure (RIFLE) or stage 3 (AKIN/KDIGO) | Increase in serum creatinine to 3 times baseline OR Increase in serum creatinine by >0.5 mg/dL to >4 mg/dL OR Urine output of <0.3 mL/kg/hour for >24 hours or anuria for >12 hours OR Initiation of kidney replacement therapy | Increase in serum creatinine to >300% baseline OR Increase in serum creatinine by >0.5 mg/dL to ≥4 mg/dL OR Urine output of <0.3 mL/kg/hour for >24 hours or anuria for >12 hours OR Initiation of kidney replacement therapy | Increase in serum creatinine to ≥3 times baseline OR Increase in serum creatinine of ≥0.3 mg/dL to ≥4 mg/dL¶ OR Urine output of <0.3 mL/kg/hour for ≥24 hours or anuria for ≥12 hours OR Initiation of kidney replacement therapy |
| Loss (RIFLE) | Need for kidney replacement therapy for >4 weeks | ||
| End stage (RIFLE) | Need for kidney replacement therapy for >3 months | ||
RIFLE: risk, injury, failure, loss, ESKD; AKIN: Acute Kidney Injury Network; KDIGO: Kidney Disease: Improving Global Outcomes; ESKD: end-stage kidney disease.
* AKIN and KDIGO provided both diagnostic and staging criteria. RIFLE provided a graded definition of AKI that is implicit in the staging criteria.
¶ In patients <18 years, stage 3 AKI is also defined by KDIGO as a decrease in estimated glomerular filtration rate (eGFR) to <35 mL/min/1.73 m2.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
