Centroblast variant of diffuse large B-cell lymphoma in a lymph node biopsy

Tumor cells show large round or oval nuclei with multiple membrane-bound nucleoli (arrow) and scanty cytoplasm. Hematoxylin and eosin, 100x magnification.

Reproduced with permission from: Sun T. Clinical application, case 32 diffuse large B-cell lymphoma. In: Flow Cytometry, Immunohistochemistry, and Molecular Genetics for Hematologic Neoplasms, 2nd ed, Lippincott Williams & Wilkins, Philadelphia 2012. Copyright © 2012 Lippincott Williams & Wilkins. www.lww.com.

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Centroblast variant of diffuse large B-cell lymphoma in a lymph node biopsy