Benefit of PEG-rHuMGDF in myelosuppressed mice

Effect of PEG-rHuMGDF (red lines) or placebo (blue lines) on the platelet, white blood cell (WBC), and red blood cell (RBC) counts in mice treated with a combination of carboplatin and sublethal irradiation. Mice treated with PEG-rHuMGDF had accelerated recovery of all blood cell lineages and reduced mortality (15 versus 94 percent).