Fibrillary glomerulonephritis EM

Electron micrograph in fibrillary glomerulonephritis showing intramembranous and subendothelial fibrillary deposits (arrows). The glomerular basement membrane (GBM) is markedly disrupted by the infiltrating fibrils and a distinct lamina densa cannot be seen.

Electron micrograph of a normal glomerular capillary loop showing the fenestrated endothelial cell (Endo), the glomerular basement membrane (GBM), and the epithelial cells with its interdigitating foot processes (arrow). The GBM is thin, and no electron-dense deposits are present. Two normal platelets are seen in the capillary lumen.