Indications and potential indications for thrombolytic therapy in venous thromboembolism
Indications and potential indications for thrombolytic therapy in venous thromboembolism
Indication
High-risk (massive) PE (ie, presence of hypotension related to PE)*
Potential indication
Patients with severe right ventricular dysfunction due to PE (ie, intermediate risk PE)
Others:
Presence of severe hypoxemia (particularly in those with a contribution from concomitant cardiopulmonary disease)
Patients with acute PE who appear to be decompensating but are not yet hypotensive
Extensive clot burden
PE: pulmonary embolism.
* This indication is widely accepted; the other potential indications require careful review of the risks of thrombolytic therapy and potential benefits.