Reprogramming adult cells to become pluripotent cells
Reprogramming adult cells to become pluripotent cells
The introduction of defined factors (as genes, mRNA, or a combination with small molecules) permits the gradual reversion of a mature, somatic cell, such as a skin fibroblast, to an induced pluripotent (iPS) cell. Sequential changes in the targeted cell are thought to proceed in an orderly manner as indicated.