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Parainfluenza gene maps

Parainfluenza gene maps
Gene maps of PIV, not to exact scale. Each negative-sense genome is drawn 3' to 5', which is the direction of gene transcription. Each encoded messenger RNA (mRNA) is shown as a rectangle; those encoding the envelope-associated proteins are shaded gray. The letter(s) within each rectangle identify the encoded protein(s); for the P gene, the protein encoded by the unedited mRNA is listed first. Nucleotide lengths are under each diagram; those representing extragenic leader, trailer, and intergenic regions are underlined. Amino acid lengths are shown above the line.
PIV: parainfluenza viruses; le: leader; N: nucleocapsid protein; P: phosphoprotein; C: C protein; D: D protein; M: matrix protein; F: fusion glycoprotein; HN: hemagglutinin-neuraminidase glycoprotein; L: polymerase protein; tr: trailer.
* PIV-3 also encodes a V protein, possibly using ribosome frameshifting.
Modified with permission from: Karron RA, Collins PL. Parainfluenza Viruses. In: Fields Virology, 5th Edition, Knipe D, Howley P (Eds), Lippincott Williams & Wilkins, Philadelphia 2006. Copyright © 2006 Lippincott Williams & Wilkins. www.lww.com.
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