Proposed mechanisms of vascular occlusion in sickle cell disease
Proposed mechanisms of vascular occlusion in sickle cell disease
Panel A (on left) illustrates adhesion of sickle cells to the vascular endothelium in post-capillary venules and venules. Panel B (on right) illustrates the subsequent trapping of dense red cells (in blue) in the partially obstructed post-capillary venules, followed by retrograde obstruction.
Graphic 80615 Version 1.0
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