Leading categories of birth defects

Birth defects	Estimated incidence
Structural/metabolic
Heart and circulation	1 in 115 births
Muscles and skeleton	1 in 130 births
Club foot	1 in 735 births
Cleft lip/palate	1 in 930 births
Genital and urinary tract	1 in 135 births
Nervous system and eye	1 in 235 births
Anencephaly	1 in 8000 births
Spina bifida	1 in 2000 births
Chromosomal syndromes	1 in 600 births
Down syndrome (trisomy 21)	1 in 900 births
Respiratory tract	1 in 900 births
Metabolic disorders	1 in 3500 births
PKU	1 in 12,000 births
Congenital infections
Congenital syphilis	1 in 2000 births
Congenital HIV infection	1 in 2700 births
Congenital rubella syndrome	1 in 100,000 births
Other
Rh disease	1 in 1400 births
Fetal alcohol syndrome	1 in 1000 births

Note: All numbers are based on the best available estimates, which underestimate the incidence of many birth defects.

PKU: phenylketonuria; HIV: human immunodeficiency virus.

Unpublished review of the literature and information from various state and regional birth defects surveillance systems (California, Iowa, Metropolitan Atlanta, New York, and Texas). http://www. marchofdimes.com/aboutus/680_2164.asp Copyright © 2000 March of Dimes Perinatal Data Center. Used by permission.

Graphic 79937 Version 3.0

خرید پکیج

Leading categories of birth defects