Platelet kinetic studies were performed in patients with a variety of hematologic conditions:
- Bone marrow hypoplasia (Hypo)
- Vitamin B12 deficiency (B12 def)
- Congestive splenomegaly (Congest)
- Immune thrombocytopenia (ITP)
- Chronic inflammation (Inflam)
- Essential thrombocythemia (ET)
Right panel – Platelet survival was significantly different from normal only in ITP.
Data from: Harker LA, Finch CA. Thrombokinetics in man. J Clin Invest 1969; 48:963.