Cutaneous findings in severe bullous erythema multiforme and Stevens-Johnson syndrome/toxic epidermal necrolysis

Bullous erythema multiforme

Detachment less than 10 percent of BSA plus

Typical targets or

Raised, atypical targets

Stevens-Johnson syndrome

Detachment less than 10 percent of BSA plus

Widespread macules or

Flat, atypical targets

Overlap Stevens-Johnson syndrome/toxic epidermal necrolysis

Detachment between 10 and 30 percent of BSA plus

Widespread macules or

Flat, atypical targets

Toxic epidermal necrolysis

With spots or without blisters

Detachment of greater than 30 percent of BSA plus

Widespread macules or

Flat, atypical targets

Without spots

Detachment greater than 10 percent of BSA with large epidermal sheets and

Without any macules or targets

BSA: body surface area.

Adapted from Bastuji-Garin S, Rzany B, Stern R, et al. Arch Dermatol 1993; 129:92.

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