BMD and bone turnover markers are independent predictors of hip fracture risk
BMD and bone turnover markers are independent predictors of hip fracture risk
Low BMD was defined according to the WHO guidelines, ie, by a value 2.5 SD or more below the young-adult mean (T-score ≤2.5). High bone resorption was defined by CTX or free D-Pyr values higher than the upper limit (mean +2 SD) of the premenopausal range. Females with both low hip BMD and high bone resorption were at a higher risk of hip fracture than those with either low hip BMD or high bone resorption.
BMD: bone mineral density; CTX: C-telopeptide; D-Pyr: free deoxypyridinoline; SD: standard deviation; WHO: World Health Organization.