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Variants of classic Reed-Sternberg cells

Variants of classic Reed-Sternberg cells
Left panel: two binucleated diagnostic Reed-Sternberg cells are seen in this field. Right upper panel: two uninucleate cells are shown. Right lower panel: multilobated nuclei or multinucleated cells are seen. Note the nuclear similarities in all three fields (ie, prominent central nucleolus with surrounding clear area).
From Warnke, RA, Weiss, LM, Chan, JK, Cleary, ML, Dorfman, RF. Tumors of the lymph nodes and spleen. Atlas of tumor pathology (electronic fascicle), Third series, fascicle 14, 1995, Washington, DC. Armed Forces Institute of Pathology.
Graphic 77200 Version 1.0

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