Strong inhibitors | Moderate inhibitors | Strong inducers | Moderate inducers |
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* Mifepristone is a significant inhibitor of CYP3A4 when used chronically (eg, for hyperglycemia in patients with Cushing syndrome); not in single-dose use.
¶ Classified as a weak inhibitor of CYP3A4 according to FDA system.[1]
Δ Classified as a weak inducer of CYP3A4 according to FDA system.[1]
◊ The fixed-dose combination therapy pack taken in the approved regimen has moderate CYP3A4 induction effects. When elagolix is used as a single agent, it is a weak CYP3A4 inducer. Norethindrone and estradiol are not CYP3A4 inducers.Data from: Lexicomp Online (Lexi-Interact). Copyright © 1978-2024 Lexicomp, Inc. All Rights Reserved.
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