Symptoms |
Duration of morning stiffness |
Pain score (visual analogue scale) |
Fatigue - severity (visual analogue scale) |
Patient's global score of disease activity (visual analogue scale) |
Physical examination |
Number of swollen joints |
Number of tender joints |
Degree of swelling and/or tenderness |
Extraarticular disease: |
Minor: nodules, episclertis, pure sensory neuropathy, pleruropericardial disease |
Major: vasculitis, Felty syndrome, motor neuropathy, interstitial lung disease |
Laboratory |
Elevated erythrocyte sedimentation rate (ESR) |
Increased C-reactive protein (CRP) |
Anemia (in the absence of chronic blood loss or hematuria) |
Leukocytosis |
Thrombocytosis |
Abnormal liver function tests (low albumin, raised alkaline phosphate) in the absence of drug toxicity or liver disease |
Inflammatory joint fluid (high polymorph count, low complement, fibrin) |
Imaging |
Low bone mineral density (juxtaarticular, vertebrae, pelvis) in absence of glucocorticoid therapy or known cause |
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