T cell-mediated hypersensitivity reactions (Gell and Coombs types IVa to IVd)

IFN-gamma: interferon-gamma; TNF-alpha: tumor necrosis factor-alpha; Th1: T helper type 1; IL: interleukin; Th2: T helper type 2; CTL: cytotoxic lymphocyte; GM-CSF: granulocyte monocyte colony-stimulating factor; PMN: polymorphonuclear cell; AGEP: acute-generalized exanthematous pustulosis.

Reproduced with permission from: Celik G, Pichler WJ, Adkinson NF Jr. Drug Allergy. In: Middleton's Allergy Principles & Practice, 7th ed, Adkinson NF, et al (Ed), Mosby Elsevier, Philadelphia 2009. p.1205-1226. Illustration used with the permission of Elsevier Inc. All rights reserved.

Graphic 75626 Version 8.0

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