Flow cytometry studies in Hereditary xerocytosis

Distribution histograms for red blood cell volume (mean corpuscular volume) and mean cell hemoglobin concentration in a normal control (top) and a patient with hereditary xerocytosis (bottom). Hereditary xerocytosis is characterized by a shift of the mean corpuscular (red cell) volume to higher values, which is indicative of the presence of reticulocytes and younger cells, and of the mean cell hemoglobin concentration to higher values, which is indicative of the presence of hyperchromic cells.