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تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Vesiculopustular lesions in neonates and infants that require treatment and/or monitoring

Vesiculopustular lesions in neonates and infants that require treatment and/or monitoring
Condition Clinical features Significance
Infectious conditions
Congenital herpes simplex virus (HSV) Grouped or single vesicles on erythematous base in crops on skin and mucous membranes; lesions usually appear between 1 and 2 weeks of age; may be associated with nonspecific signs of serious illness: temperature instability, respiratory distress, poor feeding, lethargy Requires antiviral therapy; significant morbidity and mortality if untreated
Neonatal varicella zoster virus Grouped or single vesicles on erythematous base in crops on skin and mucous membranes Requires antiviral therapy; associated with significant morbidity and mortality
Congenital syphilis Blisters, erosions that frequently involve the palms and soles; other manifestations include rhinitis, anemia, jaundice, hepatomegaly Requires antibiotic therapy; late manifestations in untreated infants may include central nervous system, skeletal, and dental abnormalities; hearing loss; and interstitial keratitis
Staphylococcal pustulosis Erythematous papules, pustules, honey-colored crusts often in areas of trauma Requires antibiotic therapy; Gram stain and culture of lesions should be obtained; may be associated with systemic/invasive infection
Staphylococcal scalded skin syndrome (SSSS) Fever, irritability, diffuse blanching erythema, flaccid blisters; positive Nikolsky sign* Requires antibiotic therapy; cultures should be obtained from any suspected focus of infection (eg, blood, urine, nasopharynx, umbilicus)
Streptococcal infections May mimic staphylococcal infections Same as for staphylococcal pustulosis and SSSS
Listeria Pustules of the skin and mucus membranes may be present in early onset disease (<7 days of age) Requires antibiotic therapy; may be associated with septicemia and/or meningitis
Candidiasis Erythematous macules and papules evolving to pustules and vesicles Requires antifungal therapy; has the potential to disseminate via the bloodstream in susceptible hosts
Congenital disorders
Epidermolysis bullosa Blister development with little or no trauma Management involves prevention of trauma, careful wound care, and treatment of infection
Epidermolytic hyperkeratosis Widespread blistering and erythema and or hyperkeratosis; denuded areas of skin Increased susceptibility to cutaneous infection
Aplasia cutis congenita Erosions present at birth that re-epithelialize to form hypertrophic or atrophic scar; involves the epidermis and dermis May be associated with other disorders (eg, trisomy 13, 4p-)
Incontinentia pigmenti Four stages that may occur simultaneously: linear streaks of erythematous papules and vesicles; warty papules or plaques in linear or swirling patterns; swirled; hypopigmented patches or streaks Majority of cases associated with neurologic, ocular, dental, and structural abnormalities
Miscellaneous
Scabies May be seen in infants as young as 3 to 4 weeks of age but never present at birth; vesicles, pustules, and papules; rare burrows on hands, feet, trunk, genitalia Requires treatment with scabicide and measures to prevent spread
Cutaneous mastocytosis Bullous eruptions with hemorrhage; positive Darier sign Requires symptomatic therapy and avoidance of triggers
* Nikolsky sign: Separation of the upper dermis and wrinkling of the skin with application of gentle pressure.
¶ Darier sign: Urticaria and erythema with rubbing, scratching, or stroking.
Graphic 75417 Version 7.0

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