Version June 2024
| Hb S polymer formation |
| Sickle cell deformability |
| Sickle cell whole blood viscosity |
| Fraction of dense irreversibly sickled cells |
| Red blood cell function |
| Sickle cell adherence to vascular endothelium |
| Endothelial cell activation |
| Mast cell activation |
| Hemostatic activation |
| Platelet activation |
| White blood cell numbers and activity |
| Vasoregulatory factors |
| Vascular architecture |
| Environmental factors |
| Psychosocial adaptation |
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