Polyclonal gammopathy

(A) Densitometer tracing of these findings reveals a broad-based peak of gamma mobility. This pattern is most often due to the presence of an inflammatory or reactive process, such as chronic liver disease, connective tissue disease, chronic infection, or a lymphoproliferative disorder.
(B) A polyclonal pattern is seen on serum protein electrophoresis on agarose gel (anode on left). The band at the right (red asterisk) is broad, and extends throughout the gamma mobility area.