Version May 2024
| Tumor characteristics |
| Clinical features |
| Indistinct borders* |
| Recurrent tumor* |
| Tumor location – Overlying nerves, corners of the mouth, vermillion border, inner canthi, lid margin, the free margin of the nasal alae, and the auditory canal* |
| Size greater than 1 cm on the face |
| Pathologic features |
| Morpheaform, sclerosing, infiltrative, perineural invasion |
| Patient characteristics |
| Darkly pigmented skin |
| Cosmetically sensitive patient* |
| Previous poor response to cryotherapy |
| Unable to care for wound |
| Cold urticaria, Raynaud phenomenon (selected sites), cold intolerance, cryofibrinogenemia, or cryoglobulinemia* |
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