Summary of immunohistochemical staining of dermatofibrosarcoma protuberans (DFSP) and other spindle cell dermal tumors

	CD34	XIIIa	S-100	SMA	Desmin	Vimentin	CD44	Hyaluronate
DFSP	+	–	–	–	–	+	+/–	+
Dermatofibroma	–	+	–	+	–	+	+*	+/–*
Nodular fasciitis	–	–	–	+	–	–
Nerve sheath tumors	+/–	–	+	–	–	–
Fibrosarcoma	–	–	–	+	–	+
Malignant fibrous histiocytoma	+/–	–	–	–	+/–	+

SMA: smooth muscle actin; +: more than 80 percent of cases staining; –: less than 20 percent of cases staining; +/–: variable staining.
* For dermatofibromas, cells stain intensely with CD44 while the stroma stains faintly for hyaluronate; DFSPs are strongly positive for hyaluronate while CD44 staining is diminished or absent.

Derived from: Haycox CL, et al. J Am Acad Dermatol 1997; 37:438 and Calikoglu E, et al. J Cutan Pathol 2003; 30:185.

Graphic 73370 Version 3.0

خرید پکیج

Summary of immunohistochemical staining of dermatofibrosarcoma protuberans (DFSP) and other spindle cell dermal tumors