Inhibitors of P-gp | Inducers of P-gp | |
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P-gp: P-glycoprotein; US FDA: US Food and Drug Administration.
* Mifepristone is a significant inhibitor of P-gp when used chronically (eg, for hyperglycemia in patients with Cushing syndrome); not in single-dose use.
¶ The combination of ombitasvir-paritaprevir-ritonavir plus dasabuvir (Viekira Pak) is not a significant inhibitor of P-gp efflux pump.[3]
Δ Minor clinical effect or supportive data are limited to in vitro effects (ie, clinical effect is unknown).Data from: Lexicomp Online (Lexi-Interact). Copyright © 1978-2024 Lexicomp, Inc. All Rights Reserved.
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